99% API CAS 88255-01-0 Nevirapine Pharmaceutical Raw Materials

99% API CAS 88255-01-0 Nevirapine pharmaceutical raw materials

Nevirapine
CAS 88255-01-0
Name: Netobimin
Molecular formula: C14H20N4O7S2
Molecular weight: 420.4612

[physicochemical properties]
Refractive index: 1.621
Density: 1.48g/cm3

Nevirapine is a non nucleoside reverse transcriptase inhibitor (Non-Nucleoside Reverse Transcriptase Inhibitor, NNRTI) of HIV-1. Nevirapine was directly linked to the reverse transcriptase of HIV-1 and blocked the RNA dependent and DNA dependent DNA polymerase activity by breaking the catalytic end of the enzyme.

Indications
Nevirapine combined with other antiretroviral drugs is used to treat H IV -1 infection. Using this drug alone will soon produce the same drug-resistant virus. Therefore, nevirapine should be used in conjunction with at least two other antiretroviral drugs. Nevirapine could prevent mother to child transmission of H IV -1 in pregnant women who did not use antiretroviral therapy during childbirth. Nevirapine can be used alone to prevent mother to child transmission. Pregnant women only need a single dose of nevirapine, and neonate should be given a single dose within 72 hours after birth.

  99% API CAS 88255-01-0 Nevirapine pharmaceutical raw materials

Nevirapine
CAS 88255-01-0
Name: Netobimin
Molecular formula: C14H20N4O7S2
Molecular weight: 420.4612

[physicochemical properties]
Refractive index: 1.621
Density: 1.48g/cm3

Nevirapine is a non nucleoside reverse transcriptase inhibitor (Non-Nucleoside Reverse Transcriptase Inhibitor, NNRTI) of HIV-1. Nevirapine was directly linked to the reverse transcriptase of HIV-1 and blocked the RNA dependent and DNA dependent DNA polymerase activity by breaking the catalytic end of the enzyme.

Indications
Nevirapine combined with other antiretroviral drugs is used to treat H IV -1 infection. Using this drug alone will soon produce the same drug-resistant virus. Therefore, nevirapine should be used in conjunction with at least two other antiretroviral drugs. Nevirapine could prevent mother to child transmission of H IV -1 in pregnant women who did not use antiretroviral therapy during childbirth. Nevirapine can be used alone to prevent mother to child transmission. Pregnant women only need a single dose of nevirapine, and neonate should be given a single dose within 72 hours after birth.

 

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