Cholesterol-lowering drugs reduce breast cancer risk and mortality
August 31, 2017 Source: Xinhua News Agency
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];A 14-year study in the UK found that women who had high cholesterol levels and took cholesterol-lowering drugs had a lower risk of breast cancer and therefore death, suggesting that cholesterol-lowering drugs may be associated with lowering breast cancer risk.
The researchers selected more than 16,000 female inpatients aged 40 or older who had been diagnosed with high cholesterol levels from January 1, 2000 to March 31, 2013, and the same number of women in the same age group. Data on female inpatients with normal cholesterol levels. By 2013, the researchers tracked them and obtained their breast cancer and deaths through the National Bureau of Statistics.
The study found that women with higher cholesterol levels were 45% less likely to develop breast cancer than those with lower cholesterol levels, and cholesterol levels were lower after excluding factors including age, gender, ethnicity, and other causes of death. High breast cancer patients are 40% less likely to die.
Researchers say that previous studies have shown that cholesterol levels are associated with breast cancer, and this finding has shown that people with higher cholesterol levels have lower risk of breast cancer, and thus have lower mortality rates, indicating some sort of The existence of a protective mechanism, which is likely to be related to cholesterol-lowering drugs.
The study's lead author, Paul Carter, said that previous studies and other related animal studies have shown that statin-lowering cholesterol-lowering drugs reduce the risk of breast cancer, and new research confirms that hospitalized women diagnosed with high cholesterol levels have breast cancer. The odds are low, so it can be inferred that the use of cholesterol-lowering drugs prevents breast cancer and reduces mortality.
Carter said they are preparing a clinical assessment of the protective effects of statins on breast cancer patients. At present, statins can be used as prescription drugs for breast cancer patients with high cholesterol levels, high-risk groups of cardiovascular diseases, and patients, but they cannot be used to prevent and treat breast cancer. If the clinical evaluation has positive results, this situation may be changed.
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