It is not surprising to simply develop biomedical materials or three-dimensional (3D) printed bioactive materials with antibacterial properties, but 3D printing biomedical materials with special antibacterial properties are used in clinical treatment and health care through rigorous testing. The bottlenecks and challenges facing the academic community. At the 4th China-ASEAN International Stomatology Summit and Cooperation Forum held recently, Prof. Yi Jin, Professor of the University of Groningen (WJKolff Institute) at the University of Groningen Medical Center in the Netherlands, introduced his research. The latest research results of the team. At present, the 3D printed antibacterial material developed by the team has entered the pre-clinical testing stage. Once the material enters industrial production, it can even produce orthoses with color and odor.
It is understood that up to now, the world-known biomaterials that can be 3D printed and can be used for long-term oral health care and treatment are rare, and the clinical "lifetime" is no more than 30 hours.
"Different from biomaterials used in the skin or in the body, the level of cytotoxicity and biocompatibility assessment of biomaterials for oral cavity is the highest and most stringent, and must be at the level of 'International Food and Drug Testing'. “Yi Yijin introduced that the 3D printing materials developed by the team with antibacterial properties have great potential for clinical application. These performances in the laboratory are “perfect†and have entered the pre-clinical testing stage.
According to reports, these new polymer materials have extraordinary contact bactericidal properties, that is, as long as the oral pathogens come into contact with the material, they will be killed, which effectively overcomes the limitations of the timeliness of the antibacterial properties of traditional biological materials. At present, the material has been used in the 3D printing antibacterial invisible appliance in orthodontic treatment. From the feedback of patients, parents and doctors, the evaluation is very high.
Current, 3D printing technology has received preliminary applications in the medical field medical model, biomimetic tissue repair, and other surgical instruments. In the oral clinical aspect, 3D printing technology can print high-precision oral models by intra-oral scanning and three-dimensional modeling of the patient's oral cavity. This technology is revolutionizing the replacement of traditional plaster dental molds.
"But modeling is only the beginning. The potential and prospects of 3D printing for oral therapy still have a very broad space." Ren Yijin also said that with the appliance as an example, in the near future, with the continuous 3D printing technology With maturity and cost reduction, doctors can even use computer software to design the appliance directly according to the condition and invite patients to participate in the design details. After both parties are satisfied, the patient can print the appliance directly at home using a 3D printer to achieve real Personalized oral therapy services.
“Perhaps, you can also ask the doctor to adjust the color, smell and personality of the appliance. At present, our materials have attracted the attention of several international companies including 3M. Once the antibacterial materials suitable for 3D printing can be industrialized Various additional requirements such as the above can be achieved." Ren Yijin said.
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packaging: 5 pcs of mask in one sealed printed plastic bag to ensure hygiene or 10pcs per box
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