A new study published in "Cell" on March 23 found that eliminating "retired" cells in the body can eliminate the damage caused by aging, which brings hope to new life extension treatments.
The researchers used a substance to treat mice that cleared cells that went to sleep due to DNA damage. The treated mice were regenerated and their kidney function improved, running twice as long as untreated mice.
The team is evaluating whether the lifespan of these mice has also been extended, and plans to conduct a series of safety studies in humans with the ultimate goal of testing whether these so-called aging cells can reverse some of the aging-related diseases.
This discovery makes it possible for doctors to treat aging itself in the future, rather than dealing with various diseases that come with aging.
Peter de Keizer, a 36-year-old scientist at the Erasmus University Medical Center in the Netherlands, said that this seemingly sci-fi scene has been scientifically supported. He said: "Maybe when people reach the age of 65, they go to the clinic every 5 years. Aging injection. I think it can be achieved when we reach this age."
As we age, DNA damage accumulates in cells, and beyond a certain threshold, it can no longer be repaired. At this point, the cells will become cancerous, self-destructive or enter a semi-dormant state. People initially thought that these aging cells were only neutral bystanders, without any biological function, but also harmless.
However, about a decade ago, this view changed.
De Keizer said: "These aging cells produce a lot of rubbish and have a negative impact on the body." He likens these cells to students in the classroom who are disturbed by the students.
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