The gene sequencing market is growing fast and the reagents are in a monopoly!
National Standard Material Resource Platform : The domestic gene sequencing market is growing rapidly. The upstream instrument reagent supplies form a monopoly pattern of foreign giants. The cost constraints and restrictions on downstream service enterprises are large, and domestic manufacturers are actively seeking breakthroughs. From the current point of view, due to the low threshold of the sequencing industry, it is expected that a form of survival of the fittest will be formed in the future.
Gene sequencing is a novel gene detection technology that can analyze the complete sequence of genes from blood or saliva, predict the possibility of multiple diseases, and the individual's behavioral characteristics and behaviors, such as cancer or leukemia, sports talent, and alcohol consumption. Gene sequencing related products and technologies have evolved from laboratory research to clinical use. It can be said that gene sequencing technology is the next technology to change the world.
In terms of China's current industrial structure, the upstream instrumental reagents have formed a monopoly pattern of foreign giants, and domestic manufacturers are actively seeking breakthroughs. For example, the sequencing instruments produced by Huada Gene, Berry and Kang, Daan Gene, and Huainkang have already been produced. Obtained CFDA approval. Since there are fewer manufacturers of gene sequencing instruments and the sealing mechanism of the sequencing instrument platform is strong, it is necessary to purchase matching reagents and consumables from suppliers to be perfectly used. Therefore, the cost of the upstream monopolistic products to the downstream service enterprises is The limit is larger.
Due to the low barriers to entry, the sequencing service industry is currently a mixed bag. The ability to interpret sequencing data is generally insufficient. It is currently in the reshuffle stage. It is expected that a group of companies will be dumped in the future, and some relatively good companies will gradually emerge and gradually form themselves. s brand.
As the hospital grasps the end customer resources, it is in a two-way strong position in the entire medical industry. Therefore, whether the gene sequencing service provider adopts a third-party independent laboratory or adopts a hospital-to-hospital mode of collaboration and collaboration, the right to speak is relatively weak relative to the hospital. At present, in the case of fewer hospitals with high-throughput sequencing pilot qualifications, the number of similar gene sequencing service providers in the market is much higher than that of powerful channel vendors in the face of the same hospital entrance. Therefore, enterprises with better channel resources and government background can obtain better hospital application portals, and in the future can better achieve downstream penetration.
Downstream is the end user of the product, such as hospitals, pharmaceutical companies, government research institutions, and so on.
According to BBC Research, the market size of instrument consumables in 2011 is about 1.6 billion US dollars, estimated to be 2.2 billion US dollars in 2016, compound growth rate (CAGR) is 6.6%; the market for sequencing services in 2011 is 988 million US dollars, expected 2016 The annual growth rate was 3.5 billion US dollars, and the compound growth rate (CAGR) was 28.8%. The sequencing data explained that the market size in 2011 was 410 million yuan, and it is expected to be 884 million US dollars in 2016, with a compound growth rate (CAGR) of 16.6%.
It can be seen that before the launch of the revolutionary product on the upstream instrument side, the growth rate of the future sequencing products and services market is expected to be: sequencing service > data analysis > instrument consumables. The fastest growth rate of sequencing services will lead the market; the data analysis market has a small base and a large growth space. Therefore, the sequencing service providers (sequencing service data analysis) in the midstream of the industry are expected to enjoy the industry feast and promote the continued prosperity of the industry.
The sequencing service achieves clinical value and produces the greatest added value. Compared with the upstream instrument provider, the sequencing service provider is the main body to realize the clinical value of the test project. Mature standardized sequencing services should include a complete set of “sequencing data analysis and clinical interpretation reportâ€, the final service is to help doctors make clinical decisions, that is, mature genetic sequencing projects must have relatively accurate clinical significance and clinical Value can be a big market in the clinical application side.
Gene sequencing is the whole of precision medicine, and it is also a relatively mature industry. It has been widely concerned. At present, gene sequencing technology has been developed to three generations.
From the comprehensive comparison of the current three-generation gene sequencing technology, the first-generation and second-generation sequencing technologies are currently widely used in the fields of scientific research and clinical medicine. The second-generation sequencing technology has obvious comparative advantages and a large market space.
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