New weapon for women to prevent HIV infection: vaginal davivirine ring

Release date: 2016-07-26


A medical device called the dapivirine ring was recently unveiled at the 2016 International AIDS Conference in Durban, South Africa. This white ring may become a powerful weapon against the HIV epidemic.

Two independent clinical trials have shown that the dapivirine ring can effectively reduce the risk of HIV infection by one-third. A recent analysis shows that among continuing users (ie women who use it every month), the risk of HIV infection can be reduced by 56%, while in the most frequently used women, the risk of HIV infection can be reduced by 75% or even More.

At least 36.7 million people are currently infected with HIV, and diseases caused by HIV become AIDS. Since 2000, HIV and AIDS have caused at least 25 million deaths. HIV infection remains a major cause of death among women aged 15-44.

HIV can be transmitted through blood and other body fluids. HIV can cause loss of immunity by attacking the human immune system. If left unchecked, the infected person will develop AIDS.

This ring is about 5 cm in diameter and is infused with a drug, similar to a vaginal ring that can be used to prevent the release of hormones. This ring is placed in the female vagina and can release the antiretroviral drug dapivirine for 30 days. After 30 days, it is removed and the new davivirine ring is repositioned.

Antiretroviral therapy is a combination of treatments that inhibit HIV reproduction and attack the human immune system. These drugs have been used to treat HIV infection since the 1990s, but recently doctors have begun to use these drugs for HIV infection prevention in high-risk populations. .

In the United States, the best HIV infection prevention drug is Truvada, a pre-exposure prophylaxis drug approved in 2012. Most of the users are men who have sex with men.

In sub-Saharan Africa, the high-risk population of HIV/AIDS is very different and the situation is even more tragic. This area is home to 24.7 million HIV carriers, with 1.1 million people dying every year from AIDS.

In recent years, HIV infection rates among young people and women have increased. According to the AIDS prevention charity AVERT, more than 4 out of every 10 new HIV-infected people are young people aged 15-24.

Young women are a type of person who is particularly vulnerable to infection because the protection of women’s rights in this area is very bad. Women and girls in this area often have little to do with their sexual destiny, and sexual violence, marital coercion and sexual transactions fill the region. The use of condoms in this area is very low and sexual violence is very common.

Therefore, effective HIV prevention measures for women are very important.

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Source: Noble

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