Release date: 2014-12-16
Recently, a research report published in the international magazine Nature Communications, researchers from King's College London through research and development of a cold sensor, which can induce the body's skin blood vessels to respond to the cold, or can be used as a treatment for frostbite Or a new treatment for hypothermia.
The TRPA1 gene is involved in the sensitivity of pain, so researchers often use it to develop painkillers. In this study, it was first discovered that the TRPA1 gene is also involved in the cold response of the skin and blood vessels of the body; in cold weather, there are many kinds of human organisms. Mechanisms to help strengthen the core temperature of the body, the skin can respond by shrinking the blood vessels, and conversely, vasodilation is essential for the temperature of the skin to rise and stay healthy.
In this study, the researchers immersed the paws of anesthetized mice in water to expose their skin to cold conditions, and then the researchers applied mice to the cold before they were exposed to the cold and during the slow cooling process. The blood flow was measured and the results showed that the gene TRPA1 plays a role in two different pathways, which can help the mice to sense changes in the ambient temperature, which can then stimulate the contractile protection in the blood vessels, and then the mouse body The process of vasodilation is dependent on the activation of TRPA1, and vasodilation is also critical for the recovery of blood flow.
The current study reveals the key role of the TRPA1 gene in regulating the body during cold exposure, and it provides a new way for future researchers to use this gene to target to enhance the body's protective response to cold. Next, the researchers hope to explain the role of other TRP receptors in the cold response of the body's skin based on current research data, especially for large families of temperature-sensitive receptors; the researchers also said that the blood vessels will be further explained in the later stages. The relationship between exposure response and skin maintenance and body temperature.
The final researcher, Peter Weissberg, said the study could help us understand the causes and mechanisms of vasoconstriction and expansion in our body, as well as help develop targeted therapies for many vascular diseases.
Source: Bio Valley
Medical Cold Patch
Throat Pain Relief Patch
[Name] Medical Cold Patch
[Package Dimension] 36 round pieces
The pain relief patch is composed of three layers, namely, backing lining, middle gel and protective film. It is free from pharmacological, immunological or metabolic ingredients.
[Scope of Application] For cold physiotherapy, closed soft tissue only.
[Indications]
The patches give fast acting pain relief for acute and chronic tonsillitis.
[How To Use a Patch]
Please follow the Schematic Diagram. One piece, one time.
The curing effect of each piece can last for 6-8 hours.
[Attention]
Do not apply the patch on the problematic skin, such as wounds, eczema, dermatitis,or in the eyes. People allergic to herbs and the pregnant are advised not to use the medication. If swelling or irritation occurs, please stop using and if any of these effects persist or worsen.notify your doctor or pharmacist promptly. Children using the patch must be supervised by adults.
[Storage Conditions] Store below 30c in a dry place away from heat and direct sunlight.
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