A few days ago, American Process Corporation (API) from Atlanta and the Swansea University School of Medicine signed a joint development agreement (JDA) to jointly develop tissue cartilage printed with human cells and nanocellulose 3D. And use it for facial reconstruction.
It is understood that the participants of this project include the research team of Stanley University's ReconRegen and received financial support from the British Medical Research Council. The project involved multiple areas, including plastic surgeons, engineers, scientists, and American Process, a manufacturer of nanocellulose.
It is understood that Swansea University's ReconRegen team has previously demonstrated that nanocellulose is compatible with human cells and can be used as a supporting tissue structure for bioprinting. In addition, the team also showed that live cells can survive this 3D printing process.
According to this joint development protocol, cells will be mixed with various nanocellulose materials of various formulations and printed in 3D into tissue for reconstruction surgery. The goal of the project is to create tissue that conforms to the shape of the human anatomy and can be tailored to different patients. In addition, the organization needs to be able to survive indefinitely and be able to withstand the test of time and degradation. Scientists say this will be the first step towards a personalized reconstruction.
According to Iain Whitaker, the project's principal, “People are increasingly using plastic or titanium 3D printed prostheses and implants. But bio-printing based on human cells is also very promising. We are based on specific The patient's needs to print living tissue and living structures. We hope that in the future, patients who have lost their ears or nose due to trauma or cancer can use their own cells to recombine new tissue with nanocellulose. This intermediate biomaterial is us. A key component of bioprinting technology, and nanocellulose was chosen as a biomaterial because its biocompatibility, mechanical properties and structural properties support cell adhesion and growth in three dimensions."
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